--- title: "Installation Tutorial" output: rmarkdown::html_vignette vignette: > %\VignetteIndexEntry{Installation Tutorial} %\VignetteEngine{knitr::rmarkdown} %\VignetteEncoding{UTF-8} --- ## Aim Install `leo.gwas` with the most robust path first, then use fallback commands when specific dependencies fail. ## Recommended path (2026-02) ```r options(timeout = 1000000) # 1) Install pak install.packages("pak", repos = "https://cloud.r-project.org") # 2) Install leo.basic pak::pkg_install("laleoarrow/leo.basic") # 3) Use leo.basic helper to install leo.gwas dependencies with multiple CPU cores leo.basic::install_deps("leo.gwas", ncpus = 8) # 4) Install leo.gwas pak::pkg_install("laleoarrow/leo.gwas") ``` ## Fallback commands for common failures If dependency resolution is still unlucky, run the following manually and retry `leo.gwas` installation. ```r # MR-related dependencies remotes::install_github("MRCIEU/TwoSampleMR") # PLINK helper (optional; needed for local clumping workflows) # This package may occasionally fail on CI/source unpack in some environments. devtools::install_github("explodecomputer/plinkbinr") # Bioconductor dependency example BiocManager::install("minfi") # CatBoost (official binary-installation page) # https://catboost.ai/docs/en/installation/r-installation-binary-installation # Recommended binary install command as of 2026-02 (macOS universal2) pak::pak("url::https://github.com/catboost/catboost/releases/download/v1.2.8/catboost-R-darwin-universal2-1.2.8.tgz") # Equivalent remotes command example remotes::install_url( "https://github.com/catboost/catboost/releases/download/v1.2.8/catboost-R-darwin-universal2-1.2.8.tgz", INSTALL_opts = c("--no-multiarch", "--no-test-load", "--no-staged-install") ) # ggrastr fallback devtools::install_github("VPetukhov/ggrastr", build_vignettes = FALSE) ``` ## Verify installation ```r library(leo.gwas) packageVersion("leo.gwas") ``` If `library(leo.gwas)` and `packageVersion("leo.gwas")` run successfully, installation is complete. ## Notes - `catboost`, `caret`, `plinkbinr`, and some genomics packages are optional for specific functions. - If a function reports missing package errors, install only that package and rerun.